Warning - Not for beginners
In the lab, N-acetylcysteine (NAC) is used as the culture media for Candida…meaning yeast thrive with NAC. If your child has yeast overgrowth or dysbiosis, NAC is food for exactly what you don’t want to grow. It's important that a special diet be in place first.
NAC is powerful in mobilizing toxins stored in the cells but the body needs to be healed enough for actual detoxification to take place otherwise toxins will be mobilizing in your child's body without a properly functioning way to be excreted.
A special diet needs to have been implemented for several months before using NAC. Please discuss all supplementation with your healthcare practitioner.
Indications of Need
Used when someone has chronic problems with:
- Immune system dysregulation
- Poor neurological functioning
- SELF-INJURIOUS BEHAVIOR
- LACK OF FOCUS
Contraindicated for those with hyperammonemia and some other conditions so please have an efficient discussion with your healthcare practitioner.
What is N-acetylcysteine?
N-acetylcysteine (NAC) is the acetyl derivative of the amino acid cysteine.
NAC is considered to be generally well-tolerated and used for a variety of medical conditions for the past several decades.
NAC widely recognized for its role as an antidote of acetaminophen overdose.
Preclinical research studies suggest that NAC may modulate pathophysiological processes such as:
- oxidative stress
- neurogenesis and apoptosis
- mitochondrial dysfunction
- dysregulation of glutamate and dopamine neurotransmitter systems
N-acetylcysteine & Autism
In 2012, a DBPC study with 29 child with autism found a significant decrease in the irritability scores via the Aberrant Behavior Checklist Irritability Subscale (ABC-I).
In 2013, another DBPC study with 40 children with autism examined adding NAC to those on risperidone and found a decrease in irritability (ABC-I) but did not affect any of the core autism symptoms.
- In this study, it's important to understand that those on risperidone started out with a significantly higher irritability score.
In 2015, a DBPC study with 40 child with autism found a significant decrease in the irritability and hyperactivity with NAC added to resperidone treatment.
There are case studies in the literature showing improvement in core symptoms of autism with NAC treatment so it is a possibility.
Previously reported adverse effects are mild abdominal pain/discomfort, heartburn, flatulence, cramps, vomiting, and diarrhea.
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